Yes, with the right type
Brass Check Valves can be used in both horizontal and vertical pipelines. The type of valve determines the orientation. Swing valves are for horizontal lines. Spring valves work in any orientation. Example: a spring valve in a vertical line.
Swing check valves in horizontal lines
Swing Brass Check Valves are designed for horizontal pipelines. The disc swings open with flow. Gravity closes the disc. They should not be used in vertical lines. Example: a swing valve in a horizontal water line.
Swing check valves in vertical lines
Swing Brass Check Valves can be used in vertical lines with upward flow. The disc closes with gravity. They may not seal well in downward flow. Example: a swing valve in a vertical line with upward flow.
Spring check valves in any orientation
Spring Brass Check Valves work in any orientation. The spring closes the disc. They can be installed horizontally or vertically. Example: a spring valve in a vertical line.
Lift check valves in vertical lines
Lift Brass Check Valves are designed for vertical pipelines. The disc lifts with flow. Gravity closes the disc. They should not be used in horizontal lines. Example: a lift valve in a vertical steam line.
Example: horizontal water supply
A home uses a swing Brass Check Valve in a horizontal water line. It prevents backflow. Example: a safe water supply.

Example: vertical pump discharge
A pump uses a spring Brass Check Valve in a vertical discharge line. It prevents backflow. Example: a reliable pump system.
Example: vertical steam line
A steam system uses a lift Brass Check Valve in a vertical line. It prevents reverse flow. Example: an efficient steam system.
Installation considerations
Check the flow direction arrow. Install the valve in the correct direction. Follow the manufacturer's guidelines. Brass Check Valves must be installed correctly.
Pressure and temperature ratings
Brass Check Valves have pressure and temperature ratings. Choose the right rating for your system. Example: a 600 WOG valve for a water line.
Final orientation summary
Brass Check Valves can be used in horizontal and vertical pipelines. Swing valves are for horizontal lines. Spring valves work in any orientation. Lift valves are for vertical lines. Choose the right type for your pipeline. Brass Check Valves are versatile for many applications. Example: select the correct valve for your installation.